However, there has been a large push to use JS more and more for rich user friendly applications with things like KnockoutJS, AngularJS and BackboneJS on the client and Node.js on the server. Microsoft has even taken a prominent role in helping bring Node.js to a Windows environment as it started out on *nix based platforms. They have also started contributing to and including scripts in their Visual Studio project templates for jQuery.
We now have things like CoffeeScript that abstracts JS and allows users to type arguably neater code which then compiles into JS.
As I mentioned earlier there is a large focus on rich content applications which use JS to make the application quick and easy to use and frameworks like KnockoutJS, AngularJS and Backbone have popped up allowing you to create these types of applications.
My biggest concern is which one do you use? I’ve had recommendations for each one which hasn’t helped. KnockoutJS is developed by @stevensanderson who works for MS so you could say it might be best to use that as it maybe more main stream and a more common requirement for employers to see you know it. I’ve heard arguments that AngularJS & BackBone provide the ability to write a more larger scale JS application where Knockout only provides JS type data binding and validation so again this is beneficial. I also discussed with someone that they and their company evaluated all of them and decided that the learning curve was too high for each and they went with jQuery and various plugins and Mustache for binding scenarios.